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目的:比较对肺结核患者采用利福平注射液与利福平胶囊治疗的临床效果。方法:收集104例肺结核患者的临床资料,根据治疗方法分为观察组(利福平注射液治疗)与对照组(利福平胶囊治疗),各52例。结果:观察组的治疗1个月、2个月后的痰涂片阴转率、痰培阴转率显著均高于对照组,有统计意义(P<0.05);观察组治疗1个月、2个月后的病灶吸收总有效率均显著高于对照组,有统计意义(P<0.05);观察组的不良反应发生率显著低于对照组,有统计意义(P<0.05)。结论:在肺结核治疗中,相对于利福平胶囊,利福平注射液有效提高痰菌阴转率及病灶吸收率,并且能减少不良反应的发生,安全有效,值得推广。
Objective: To compare the clinical effects of rifampicin and rifampicin in patients with pulmonary tuberculosis. Methods: The clinical data of 104 patients with pulmonary tuberculosis were collected and divided into observation group (rifampicin injection treatment) and control group (rifampicin capsule treatment) according to the treatment method, each with 52 cases. Results: The sputum smear negative conversion rate and sputum negative conversion rate in the observation group were significantly higher than those in the control group at 1 month and 2 months after treatment (P <0.05). The observation group was treated for 1 month, The total effective rate of lesion absorption after 2 months was significantly higher than that of the control group (P <0.05). The incidence of adverse reactions in the observation group was significantly lower than that of the control group (P <0.05). Conclusion: In the treatment of pulmonary tuberculosis, rifampicin injection is effective and safe in reducing the negative conversion rate and the absorption rate of sputum, and is safe and effective.