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目的:观察盐酸戊乙奎醚注射液联合氯解磷定治疗混配农药中毒的治疗效果。方法:选取我院60例混配农药中毒的患者,将其随机分为观察组和对照组,每组30例,对照组使用阿托品联合氯解磷定治疗,观察组使用盐酸戊乙奎醚注射液联合氯解磷定进行治疗,观察两组药效达最好所用的时间和胆碱酯酶的活性回升至50%所用的时间。结果:观察组药效最好所用的时间明显短于对照组(P<0.05),且胆碱酯酶的活性回升至50%所用的时间明显小于对照组(P<0.05)。结论:盐酸戊乙奎醚注射液联合氯解磷定在治疗混配农药中毒患者时,具有较好的疗效,患者胆碱酯酶的活性回升较快,值得临床广泛应用。
Objective: To observe the effect of penehyclidine hydrochloride injection combined with chlorpheniramine in the treatment of mixed pesticide poisoning. Methods: Sixty patients with pesticide poisoning in our hospital were selected and randomly divided into observation group and control group, with 30 cases in each group. The control group was treated with atropine and chlorpheniramine. The observation group was injected with penehyclidine hydrochloride Liquid combined with chlorpromazine treatment, the best time to observe the two groups of drugs and cholinesterase activity rose to 50% of the time. Results: The best time of observation group was shorter than that of the control group (P <0.05), and the cholinesterase activity was recovered to 50% of the time was significantly less than the control group (P <0.05). CONCLUSION: Penehyclidine hydrochloride injection combined with chlorpromazine has a good curative effect in treating patients with pesticide poisoning. The activity of cholinesterase in patients is rapidly rising, which is worthy of clinical application.