修补鼓膜是对慢性化脓性中耳炎者重建听觉功能的重要手术,其成败与材料的选择、制备和手术技巧有密切关系。过去使用的材料及方法繁多,各具优点,但还没有一种能完全恢复穿孔鼓膜的解剖结构及生理功能。1964年Chalat首先应用新鲜尸体的无菌鼓膜修补穿孔,虽遭失败,但为鼓室成形术的取材开创了新的途径。1964年Marquet报 Repair of tympanic membrane is an important operation for the reconstruction of auditory function in chronic suppurative otitis media, its success or failure is closely related to the choice of materials, preparation and surgical skills. There are many materials and methods used in the past, each with its own advantages. However, there is no one that can completely restore the anatomy and physiology of the perforated tympanic membrane. In 1964, Chalat first applied the sterile cornea of ​​the fresh corpse to repair the perforation. Although it failed, it opened up a new way for the tympanoplasty. Marquet, 1964