论文部分内容阅读
目的:探讨放疗对局限期和广泛期小细胞肺癌化疗疗效的影响。方法:用寿命表法和LogRank法分析比较61例化疗加放疗(化放组)和同期46例单纯化疗(单化组)小细胞肺癌的生存率。结果:化放组病人1、3、5年生存率分别为705%、254%和129%,而单化组分别为407%、26%和26%,两组比较有显著差异(P<001)。在局限期病人中,化放组1~5年生存率明显高于单化组(P<0025),而在广泛期病人中,化放组1~5年生存率与单化组无差异(P>005)。结论:放疗能提高局限期小细胞肺癌化疗后的生存率,而对广泛期病人的生存率无影响。
Objective: To investigate the effect of radiotherapy on the curative effect of small and medium-sized small cell lung cancer in a limited period and extensive period. Methods: Survival rates of 61 patients with chemoradiotherapy (chemotherapy group) and 46 patients with chemotherapy alone (chemotherapy group) in small cell lung cancer were analyzed by life table method and LogRank method. Results The 1, 3, 5-year survival rates of patients in the chemotherapy group were 705%, 254% and 129%, respectively, while those in the chemotherapy group were 407%, 2.6% and 2.6% %, There was a significant difference between the two groups (P <001). Among the patients with definite stage, the 1- to 5-year survival rates in the chelation group were significantly higher than those in the singulation group (P <0025). However, in the extensive group, the 1- to 5-year survival rates in the chelation group were significantly lower than those in the chemotherapy group Difference (P> 005). Conclusion: Radiotherapy can improve the survival rate after chemotherapy in patients with localized small cell lung cancer, but has no effect on the survival rate in patients with extensive stage.