目前,对慢性酒精中毒引起骨质脆弱的机制已逐渐了解。患者继发骨质疏松的发生率可高达30～40%。一般骨皮质密度正常或减弱,但骨小梁的密度则显示减低。 大量研究表明,嗜酒者不论有否肝硬变,均有骨小梁体积明显减弱以及其它一些不规则改变,如成骨细胞衰竭或过度骨钙盐形成;有的发生骨软 At present, the mechanism of bone fragility caused by chronic alcoholism has been gradually understood. The incidence of secondary osteoporosis in patients can be as high as 30 to 40%. Normal bone cortical bone density normal or weakened, but the trabecular bone density showed decreased. Numerous studies have shown that alcoholic liver cirrhosis, regardless of whether there are significantly reduced trabecular bone volume and other irregular changes, such as osteoblastic failure or excessive formation of bone calcium; and some occur soft