葡萄糖-6-磷酸脱氢酶(G-6-PD)是红细胞糖代谢中戊糖旁路酵解过程必需的一种酶,此酶缺乏是蚕豆病、伯氨喹啉溶血性贫血、部分新生儿溶血病、感染后溶血、输血后溶血及遗传性非球形细胞性溶血性贫血的内在因素。现已知G-6-PD缺乏属遗传性,遍及全世界。其发生率可因地区、民族的不同而有差异。我省蚕豆病甚多,上述其它类型的溶血也可见到。为了解我省G-6-PD缺乏的发生情况,开展对其所致疾病的预防工作,我们于1981～1982年在贵州省7个地区7种民族中进行了G-6-PD缺乏的流行病学调查,现将结果报道于下。材料与方法 Glucose-6-phosphate dehydrogenase (G-6-PD) is an enzyme necessary for pentose by-pass glycolysis in erythrocyte glucose metabolism. This enzyme deficiency is a result of broad bean disease, primaquine hemolytic anemia, Hemolytic disease, post-infection hemolysis, post-transfusion hemolysis and hereditary non-hemoglobin hemolytic anemia. It is known G-6-PD deficiency is hereditary, all over the world. The incidence may vary by region and nation. Broad bean disease in our province is much, the above other types of hemolysis can be seen. In order to understand the occurrence of G-6-PD deficiency in our province and to carry out the prevention of the disease caused by it, we conducted a G-6-PD deficiency epidemic among 7 ethnic groups in 7 regions of Guizhou Province from 1981 to 1982 Surveys, the results reported below. Materials and Methods