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[目的]比较冠脉内注射肾上腺素和维拉帕米对急性心肌梗死(AMI)患者经皮冠状动脉介入术(PCI)中慢血流的影响.[方法]回顾性分析2016年6月至2017年6月本院收治的行PCI治疗的98例AMI患者的临床资料,所有患者均行PCI术治疗.根据冠脉内注射药物的不同将其分为A组(冠脉内注射肾上腺素,n＝49)和B组(冠脉内注射维拉帕米,n＝49).比较两组患者的冠脉血流情况、血清炎性因子水平和心血管不良事件发生情况.[结果]两组患者病变血管支数情况比较,差异无统计学意义(P＞0.05).术后A组患者恢复Ⅲ级TIMI血流率显著高于B组,达到Ⅲ级TIMI血流时间低于B组,差异具有统计学意义(P＜0.05).A组PCI术后血清超敏C反应蛋白(hs-CRP)、肌酸激酶同工酶(CK-MB)水平显著低于B组,差异具有统计学意义(P＜0.05);两组血清氨基末端B型脑钠肽前体(NT-proBNP)、肌钙蛋白T(cTnT)水平比较,差异无统计学意义(P＞0.05).A组心血管不良事件发生率为6.12％(3/49)显著低于B组的12.24％(6/49),差异具有统计学意义(χ2＝7.354,P＝0.017＜0.05).[结论]心肌梗死PCI术患者术中冠脉注射肾上腺素和维拉帕米均能改善术中慢血流情况,而注射肾上腺素改善效果较佳,安全性较好.“,”[Objective]To compare the effects of intracoronary injection of adrenalin or verapamil on slow blood flow during percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI).[Methods]The clini-cal data of 98 AMI patients treated with PCI from June 2016 to June 2017 were analyzed retrospectively.All patients were treated with PCI.The patients were divided into two groups :group A(intracoronary injection of epinephrine)and group B(intracoronary injection of verapamil).The coronary blood flow,serum inflammatory factor level and cardiovascular ad-verse events were compared between the two groups.[Results]There was no significant difference in the number of vessel branches between the two groups(P ＞0.05).The recovery rate of grade Ⅲ TIMI in the group A was significantly higher than that in the group B,and the blood flow time to grade Ⅲ TIMI was lower in the group A than in the group B.The difference was statistically significant(P ＜0.05).The levels of serum hypersensitive C-reactive protein(hs-CRP)and creatine kinase isoenzyme(CK-MB)were significantly lower in the group A than the in the group B after PCI.There was no significant difference in the levels of NT-proBNP and cTnT between the two groups(P ＞0.05).The incidence of car-diovascular adverse events in the group A 6.12％(3/49)was significantly lower than that the in the group B 12.24％(6/49),and the difference was statistically significant(χ2＝7.354,P ＝0.017＜0.05).[Conclusion]Both adrenalin and vera-pamil can improve the slow blood flow in patients with myocardial infarction(PCI),while adrenalin injection has better effect and safety.