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目的:探讨注射用红花黄色素治疗冠心病心肌缺血的临床研究。方法:将2015年10月至2016年10月在清远市清城区人民医院心内科治疗的120例冠心病心肌缺血患者随机分为两组,对照组采用常规治疗,在此基础上观察组采用注射用红花黄色素治疗,比较两组患者的治疗效果、血液流变学指标。结果:观察组治疗有效率为95%,较对照组的81.67%显著提高,差异有统计学意义(P<0.05);观察组高切黏度、低切黏度、血浆黏度、纤维蛋白原及红细胞比容较对照组显著改善,差异有统计学意义(P<0.05);观察组心绞痛发作次数及发作时间均较对照组明显下降,差异有统计学意义(P<0.05)。结论:注射用红花黄色素治疗冠心病心肌缺血疗效显著,能有效缓解症状,促进心脏血液循环,降低血液黏度。
Objective: To investigate the clinical research of safflower yellow pigment in the treatment of myocardial ischemia in coronary heart disease. Methods: From October 2015 to October 2016 in Qingyuan People’s Hospital of Qingyuan City, Department of Cardiology treatment of 120 cases of myocardial ischemia in patients with coronary heart disease were randomly divided into two groups, the control group with conventional treatment, on the basis of the observation group used Injection of safflower yellow pigment treatment, the treatment effect of two groups of patients, blood rheology indicators. Results: The effective rate of observation group was 95%, which was significantly higher than that of control group (81.67%), the difference was statistically significant (P <0.05). The observation group’s high shear viscosity, low shear viscosity, plasma viscosity, fibrinogen and erythrocyte ratio (P <0.05). The number of angina pectoris and the onset time in the observation group were significantly lower than those in the control group (P <0.05). Conclusion: The effect of injection of safflower yellow pigment in treating myocardial ischemia with coronary heart disease is significant. It can effectively relieve the symptoms, promote the blood circulation of the heart and lower the blood viscosity.