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正常人口服胆囊造影剂能使血清T_3迅速下降,T_4和?T_3轻度升高,而甲亢患者口服胺碘苯丙酸(Ipodate)能使血清T_3水平明显下降,T_4中度下降.作者对5名甲亢患者每天服用与胺碘苯丙酸结构类似的碘番酸(Ippanoic Acid)1克,共21天,分别于治疗前1天和服药中1、2、4、7、14和21天取血;用放免法测定血清T_3、T_4和TSH以及T_3活性炭吸收率.结果表明,服药后1天血清T_3较服药前下降水量55%,FT_3下降50%,2天后FT_3较治疗
Normal human gallbladder contrast medium can make serum T_3 rapidly decline, T_4 and T_3 slightly increased, while patients with hyperthyroidism oral administration of amiodarone (Ipodate) can make the serum T_3 level decreased, T_4 moderate decline.Author 5 Patients with hyperthyroidism take 1 g of Ippanoic Acid, which has a similar structure to that of amiodarone, daily for 21 days, taken at 1 day before treatment and on days 1, 2, 4, 7, 14 and 21 The serum T_3, T_4 and TSH and T_3 activated carbon absorption rate were measured by radioimmunoassay.The results showed that serum T_3 decreased 55% and FT_3 decreased by 50%