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原发性结直肠癌病人基质金属蛋白酶-9(MMP-9)水平明显升高,但这种改变与痛转移是否相关尚不清楚。本文为MMP-9RNA表达可能是原发性结直肠癌复发和存活的一种强有力的独立预测因素提供了第一个证据。 研究标本来自71例原发性结直肠癌病人。所有病人均接受肿瘤切除手术。术前无一例行放疗或化疗。肿
The level of matrix metalloproteinase-9 (MMP-9) is significantly elevated in patients with primary colorectal cancer, but whether this change is related to pain metastasis is unclear. This article provides the first evidence that MMP-9 RNA expression may be a powerful independent predictor of recurrence and survival of primary colorectal cancer. The study specimens were from 71 patients with primary colorectal cancer. All patients underwent tumor resection. No preoperative radiotherapy or chemotherapy was performed. swollen