论文部分内容阅读
严重和广泛的肺纤维化使肺正常结构破坏,气体交换受阻,进而引起心脏和其他重要脏器病变。肺纤维化的病因很多,其中15～20%病因不明。Fulmer把肺纤维化病因归纳为九类:①尘肺;②药物作用;③物理因素;④细菌感染;⑤慢性肺淤血;⑥肺血管病变;⑦肿瘤;⑧先天性和家族性肺部疾病;⑨病因不明。可见,肺纤维化是多种肺部疾病的主要病变和结局,在肺部疾病中占重要地位。多年来对其发病机制进行了大量研究,综述如下。
Severe and extensive pulmonary fibrosis, the normal structure of the lung damage, blocked gas exchange, which in turn lead to heart and other important organ disease. Many causes of pulmonary fibrosis, of which 15 to 20% of the etiology is unknown. Fulmer summarized the causes of pulmonary fibrosis into nine categories: ① pneumoconiosis; ② drug effects; ③ physical factors; ④ bacterial infections; ⑤ chronic pulmonary congestion; ⑥ pulmonary vascular disease; ⑦ tumors; ⑧ congenital and familial pulmonary diseases; ⑨ The cause is unknown. Can be seen, pulmonary fibrosis is a variety of lung disease, the main lesion and outcome, occupies an important position in the lung disease. Over the years its pathogenesis carried out a lot of research, summarized as follows.
