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目的:通过对61例脑胶质瘤X刀治疗效果的临床分析,提高X刀治疗胶质瘤的认识。方法:对61树胶质瘤病人进行X刀治疗。单决治疗54例,多次治疗7倒。治疗体积5~110cm3,单次治疗周边剂量16~22Gy,分次治疗周边剂量12~16Gy,分3~6次。所有病灶80%的体积均以70~110%等剂量线覆盖肿瘤边缘。随访6~26月。结果完全缓解6例(9.84%),部分缓解29例(47.54%),无变化11例(18.03%),进展14例(22.95%),总有效率77.05%。生存期14~26月,平均21.5月。结论X刀是治疗脑胶质瘤的一种有效方法。肿瘤直径小,恶性度低疗效好;直径大,恶性度高疗效欠佳。
OBJECTIVE: To improve the understanding of X-knife treatment of glioma by clinical analysis of the therapeutic effects of 61 cases of glioma X-knife. Methods: X-knife treatment was performed on 61 patients with glioma. 54 cases were treated with single treatment, and 7 treatments were repeated. Treatment volume 5 ~ 110cm3, a single treatment of the peripheral dose of 16 ~ 22Gy, divided treatment of peripheral dose of 12 ~ 16Gy, divided 3 ~ 6 times. Eighty percent of all lesions covered the tumor margin with a 70 to 110% isodose line. Follow-up 6 to 26 months. Results Complete remission in 6 cases (9.84%), partial remission in 29 cases (47.54%), no change in 11 cases (18.03%), progress in 14 cases (22.95%), total effective rate 77.05 %. The survival period is 14 to 26 months, with an average of 21.5 months. Conclusion X-knife is an effective method for treating glioma. The tumor has a small diameter, a low degree of malignancy, a good effect, a large diameter, a high degree of malignancy, and a poor efficacy.