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目的了解新疆塔城地区手足口病病原体分布,为采取有效控制措施提供科学依据。方法通过各县(市)疾病预防控制中心和医院采集的咽拭子、粪便、疱疹液等标本,用实时荧光PCR核酸检测技术进行EV71型和CA16型肠道病毒的检测。结果共采集128份手足口病临床诊断病例标本和疑似标本,检测出肠道病毒92份,阳性率71.87%,其中EV71型病毒54份(含1例死亡病例),阳性率42.18%,CA16型病毒37份,阳性率28.90%,其他肠道病毒1例;发病年龄集中在0～5岁,散居儿童发病数多于托幼儿童,男性高于女性。结论塔城地区手足口病发病率男性高于女性,小于等于5岁组儿童明显高于其他年龄组,散居儿童发病数多于幼托儿童,病例以轻型为主,但也有少数患者出现并发症,并发展为重症病例,甚至死亡,病原以肠道病毒EV71型为主。
Objective To understand the distribution of hand-foot-mouth disease in Tacheng, Xinjiang and to provide a scientific basis for taking effective control measures. Methods The specimens of throat swab, feces and herpes fluid collected by CDC and hospitals of counties (cities) were detected by real-time fluorescence PCR for the detection of EV71 and CA16 enterovirus. Results A total of 128 clinical specimens and suspected specimens of hand-foot-mouth disease were collected. The positive rate of enterovirus 71 was 71.87%, of which 54 were EV71 (including 1 death), the positive rate was 42.18% 37 cases of virus, the positive rate of 28.90%, 1 other cases of enterovirus; age of onset concentrated in the 0 to 5 years old, the incidence of diaspora more than kindergarten children, males than females. Conclusions The prevalence of HFMD in Tacheng area is higher than that in women. The number of children less than or equal to 5 years old is obviously higher than that of other age groups. The incidence of scattered children is more than that of child care children. The cases are mainly light, but there are also a few patients with complications , And developed into severe cases, and even death, the main pathogen to enterovirus EV71 type.