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目的探讨自体血回输技术在儿童癫痫手术中的应用价值。方法回顾性分析首都医科大学宣武医院功能神经外科2014年1月至2016年12月行癫痫手术的43例患儿的临床资料。根据术中是否应用自体血回输分为自体血组和非自体血组。比较两组患者在临床特征、术中术后情况及异体输血等方面的差异。结果自体血组26例(60.5%),非自体血组17例(39.5%)。自体血组患者的年龄、身高、体重、病灶切除范围、手术时间、术中失血量均大于非自体血组,差异均有统计学意义(P<0.05)。自体血组术中输注异体红细胞者10例(38.5%),非自体血组9例(52.9%),差异无统计学意义(P=0.35)。两组患者术前、术后血红蛋白、术中血浆的输注率差异无统计学意义(P>0.05)。两组患者术中生命体征均平稳,无严重不良事件发生。结论自体血液回输可能降低术中异体红细胞的输注率,可安全、有效地应用于儿童癫痫手术。
Objective To explore the value of autologous blood transfusion in children with epilepsy. Methods The clinical data of 43 children undergoing epilepsy surgery from January 2014 to December 2016 in Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University were retrospectively analyzed. According to whether intraoperative autologous blood transfusion is divided into autologous blood group and non-autologous blood group. The clinical characteristics, intraoperative and postoperative conditions and allogeneic blood transfusion were compared between the two groups. Results There were 26 cases (60.5%) in autologous blood group and 17 cases (39.5%) in non-autologous blood group. The age, height, weight, excision range, operation time and intraoperative blood loss in patients with autologous blood were significantly higher than those in non-autologous blood (P <0.05). There were 10 cases (38.5%) of allogeneic red blood cells transfused in autologous blood group and 9 cases (52.9%) in non-autologous blood group, the difference was not statistically significant (P = 0.35). Preoperative and postoperative hemoglobin, intraoperative plasma infusion rate was no significant difference between the two groups (P> 0.05). The vital signs in both groups were stable and no serious adverse events occurred. Conclusion Autologous blood transfusion may reduce the intraoperative rate of allogeneic red blood cells infusion, safe and effective in children with epilepsy surgery.