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目的探究剖宫产术后子宫切口妊娠的临床治疗方法。方法 36例子宫切口妊娠患者按照随机原则分为观察组与对照组,每组18例。对照组采用甲氨蝶呤注射液肌内注射,观察组在阴道超声的辅助下直接向孕囊内注射甲氨蝶呤注射液稀释液。两组患者均配合早晚口服米非司酮片。比较两组患者的治疗效果和血β-人绒毛膜促性腺激素(β-HCG)转阴时间。结果观察组治疗总有效率为94.4%,明显高于对照组的66.7%,两组比较,差异具有统计学意义(P<0.05);观察组的血β-HCG转阴时间为(8.9±2.3)d,明显短于对照组的(14.2±3.1)d,两组比较,差异具有统计学意义(P<0.05)。结论在阴道超声的辅助下将甲氨蝶呤注射液稀释液直接注入孕囊可以提高治疗有效率,缩短血β-HCG转阴时间,值得临床推广。
Objective To investigate the clinical treatment of uterine incision pregnancy after cesarean section. Methods 36 cases of uterine incision pregnancy were randomly divided into observation group and control group, with 18 cases in each group. The control group was given intramuscular injection of methotrexate injection, and the observation group received methotrexate injection directly into the gestational sac with the aid of vaginal ultrasound. Two groups of patients with morning and evening oral mifepristone tablets. The therapeutic effect and β-human chorionic gonadotropin (β-HCG) negative conversion time were compared between the two groups. Results The total effective rate of observation group was 94.4%, which was significantly higher than that of control group (66.7%), the difference was statistically significant (P <0.05) ) d, which was significantly shorter than that of the control group (14.2 ± 3.1) d, the difference was statistically significant (P <0.05). Conclusions The injection of methotrexate injection diluent directly into the gestage sac with the help of vaginal ultrasound can improve the treatment efficiency and shorten the blood β-HCG negative conversion time, which is worthy of clinical promotion.