方法:由内窥镜证实的59例十二指肠溃疡的门诊病人被列为治疗对象,由其它因素(如药物、乙醇)引起的和伴有并发症的十二指肠溃疡除外。病人分为两组30例用Sucralfate、29例用甲氰咪胍,治疗前都作胃泌酸功能和血清胃泌素测定,除外胃泌素瘤。Sucralfate组和甲氰咪胍组分别在每餐前半小时及睡前服用1g和300mg,四周后复查十二指肠镜,如溃疡仍未愈 METHODS: Outpatients with 59 duodenal ulcers confirmed by endoscopy were enrolled as treated subjects except for duodenal ulcers caused by other factors (eg, drugs, ethanol) and with complications. Patients were divided into two groups of 30 patients with Sucralfate, 29 patients with cimetidine, before treatment for gastrin function and serum gastrin determination, except for gastrinoma. Sucralfate group and cimetidine group, respectively, before half an hour before meals and before taking 1g and 300mg, four weeks after the review of duodenoscopy, such as ulcers still unhealed