本文报告20例重型格林-巴利综合征的心脏损害。男14例,女6例。20例中18例已行气管切开,且有16例需要长期持续使用呼吸机维持呼吸功能。所有病例除有心脏损害外,其中15例同时并存呼吸肌麻痹和肺部感染。本组已死亡10例。笔者认为,本病的心脏损害的致病机理与肺部感染和植物神经功能障碍有关,积极防治肺部感染和植物神经功能障碍对降低心脏损害发病率和病死率均有重要意义。 This article reports the cardiac damage in 20 patients with severe Guillain-Barre syndrome. There were 14 males and 6 females. Twenty of the 20 patients underwent tracheotomy and 16 needed long-term use of a ventilator to maintain respiratory function. In addition to heart damage in all cases, 15 of them coexisted with respiratory muscle paralysis and pulmonary infection. This group has died in 10 cases. The author believes that the pathogenesis of heart disease damage and lung infection and autonomic dysfunction, and active prevention and treatment of pulmonary infection and autonomic dysfunction to reduce the incidence of heart damage and mortality are of great significance.