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目的研究乙二胺四乙酸（ＥＤＴＡ）和枸橼酸对细小根管的作用，为临床应用提供实验依据。方法甲乙两组分别对１４个离体牙细小根管用１７％ＥＤＴＡ和５０％枸橼酸处理３天。结果用１７％ＥＤＴＡ溶液经过３天处理的１４个细小根管全部有效，总有效率１００％，且扩大深入达４ｍｍ以上的有１１个根管，有９个根管达到工作长度。用５０％枸橼酸溶液经过３天处理的１４个细小根管中有效１１个，无效３个，总有效率７８．５７％，有８个根管扩大深入达４ｍｍ以上，并达到工作长度。甲乙两组的扩大深入程度，经统计学处理有显著性差异（Ｐ＜０．０１）。结论ＥＤＴＡ是化学制备细小根管的首选药物
Objective To study the effect of ethylenediaminetetraacetic acid (EDTA) and citric acid on small root canal and provide experimental basis for clinical application. Methods A and B groups were treated with 17% EDTA and 50% citrate for 14 days respectively. Results Fourteen small root canals treated with 17% EDTA solution for 3 days were all effective, with a total effective rate of 100%. There were 11 root canals extended to reach depths above 4 mm, and nine root canals reached working length. Of the 14 small root canals treated with 50% citric acid solution for 3 days, 11 were effective, 3 were ineffective, and the total effective rate was 78.57%. There were 8 root canals extending deeper than 4 mm and reaching the working length. A group of two groups to deepen the degree of expansion, the statistical analysis of significant differences (P <0.01). Conclusion EDTA is the first choice of chemical preparation of small root canal drugs