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综述了转移性鼻咽癌的各种治疗方法和研究进展,提出了全身化疗是转移性鼻咽癌的主要治疗策略。化疗应遵循个体化原则。对于体质良好的患者,可选用以铂类为基础的三药联合方案。对于体质一般患者,可选用经典FP方案,或TP、GP、DP等其他二药方案。对于铂类耐药的患者,可选用EGFR单抗分子靶向治疗。远处单个转移病灶患者,可适当考虑局部姑息性放疗。远处转移合并局部复发患者,局部病灶可考虑手术或二程放疗。对于无法承受化疗、放疗等一般状况不良的患者,可采用中医中药、临床积极支持治疗。转移性鼻咽癌的治疗模式应遵循个体化原则的综合治疗,以期提高疗效、延长患者生存时间。
Summarized the various treatment methods and research progress of metastatic nasopharyngeal carcinoma, and proposed that systemic chemotherapy is the main treatment strategy for metastatic nasopharyngeal carcinoma. Chemotherapy should follow the principle of individualism. For patients with good constitution, choose platinum-based triple-drug program. For physical general patients, the choice of the classic FP program, or TP, GP, DP and other two drug programs. For platinum-resistant patients, the choice of EGFR monoclonal antibody targeted therapy. Patients with a single distant metastasis may be considered local palliative radiotherapy. Remote metastasis combined with local recurrence patients, local lesions may consider surgery or two-way radiotherapy. For those who can not afford chemotherapy, radiotherapy and other general adverse conditions can be used traditional Chinese medicine, clinical active supportive treatment. The treatment of metastatic nasopharyngeal carcinoma should follow the principle of individualized comprehensive treatment, with a view to improving the curative effect and prolonging the survival time of patients.