了解集落刺激因子,首先要介绍造血细胞体外培养所见到的集落。人类骨髓或外周血中存在着一种最原始的细胞,称多能造血干细胞,它可以在某种造血生长因子(HGF)的刺激下,定向分化为各类造血祖细胞。由 To understand colony stimulating factors, we first need to introduce the colonies seen in the in vitro culture of hematopoietic cells. One of the most primitive cells in the human bone marrow or peripheral blood, called pluripotent hematopoietic stem cells, can be differentiated into various hematopoietic progenitor cells under the stimulation of certain hematopoietic growth factors (HGF). by