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光动力治疗 (photodynamic therapy,PDT)是一种利用光化学反应进行治疗的新技术 ,根据其对新生血管的特异性栓塞作用 ,近年来用于老年性黄斑变性 (age- related macular degeneration,AMD)治疗 ,经过大量的动物和临床试验 ,已取得一定的进展。现对 PDT的原理、基础研究以及在 AMD治疗中的临床应用作一综述。
Photodynamic therapy (PDT) is a new technology that uses photochemical reactions for the treatment of age-related macular degeneration (AMD) in recent years based on its specific embolization of neovascularization After a large number of animal and clinical trials, some progress has been made. Now the principle of PDT, basic research and clinical application in the treatment of AMD are reviewed.