本文对25例肝硬化患者进行甲状腺功能检查，包括测定、T3，T4、FT3，T3摄取率（T3U）和促甲状腺激素（TSH），并以17例慢性肝炎对照。结果表明，肝硬化患者的T3，T4，FT3和FT4水平与慢性肝炎相比均呈有意义的降低（P＜0．01），而T3U，TSH呈有意义的增高（P＜0.01）。又对5例进行促甲状腺激素释放激素（TRH）试验，TRH负荷后30分钟时TSH水平为注射前的4倍，呈有意义升高（P＜0．02），T3在TRH负荷后无变化。后又进行T3抑制试验，T3负荷后TSH值明显被抑制。 Thirty-five patients with cirrhosis were examined for thyroid function, including T3, T4, FT3, T3 uptake rate (T3U) and thyroid stimulating hormone (TSH), and 17 chronic hepatitis controls. The results showed that the levels of T3, T4, FT3 and FT4 in cirrhotic patients were significantly lower than those in chronic hepatitis (P <0.01), while T3U and TSH were significantly increased (P <0.01). Thyrotropin releasing hormone (TRH) test was also performed on 5 patients. TSH level at 4h after injection of TRH was 4 times higher than that before injection (P <0.02), while T3 did not change after TRH loading . After T3 inhibition test, TSH after T3 load was significantly inhibited.