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收集1997年2月至11月间HBsAg阳性孕产妇100例,同期收集健康孕产妇109例进行孕产妇HBV感染影响因素的病例对照研究。多因素分析表明HBV感染者接触史、频繁在外用餐、街头摊点用餐及出生于南方为孕产妇HBV感染的危险因素,乙肝疫苗接种为保护因素。分级分析表明暴露于父母HBV感染家庭的孕产妇HBV感染的估计相对危险性(16.09)分别大于暴露于同胞(6.13)、丈夫(5.11)及其他(1.84)HBV感染者。结果提示:父母HBV感染史、HBV感染家族史、频繁在外用餐、街摊用餐及出生地对孕产妇HBV感染影响较大,而经血传播并非孕产妇HBV感染的主要途径。
A total of 100 HBsAg-positive pregnant women were collected from February to November 1997, and 109 healthy pregnant women were collected during the same period to investigate the influencing factors of HBV infection in pregnant women. Multivariate analysis showed that the history of exposure to HBV infection, frequent out-of-home meals, street stalls dining and was born in the South as a risk factor for HBV infection in pregnant women, hepatitis B vaccination as a protective factor. Hierarchical analysis showed that the estimated relative risk (16.09) for HBV infection in pregnant women exposed to their parents with HBV infection was greater than that of their females (6.13), husbands (5.11) and other (1.84) By. The results suggest that the history of HBV infection among parents, the family history of HBV infection, frequent out-of-home meals, street food and birthplace have a greater impact on HBV infection in pregnant women, while menstrual transmission is not the main way of HBV infection in pregnant women.