采用自身随机交替对照方法，观察了恩丹西酮的止吐作用，４４例患者入组，顺铂剂量为５０ｍｇ／次，连用３天。患者在第一周期随机接受恩丹西酮或胃复安止吐方案，在第二周期时交替止吐方案。结果显示，恩丹西酮控制急性恶心呕吐优于胃复安方案，９５％的患者有效，而对照组仅５０％有效，恩丹西酮组没有观察到锥体外系症状，而对照组中有３例出现锥体外系症状。 Using its own random alternating control method, observed ondansetron antiemetic effect, 44 patients were enrolled, cisplatin dose of 50mg / times, once every 3 days. Patients were randomized to ondansetron or metocloptin antiemetic in the first cycle and alternated antiemetic in the second cycle. The results showed that ondansetron treatment of acute nausea and vomiting superior to metocloptin program, 95% of patients effective, while the control group was only 50% effective, ondansetron group did not observe extrapyramidal symptoms, while the control group 3 cases of extrapyramidal symptoms.