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80年代以来,分子流行病学研究表明,人群中肿瘤的遗传易感性约5％为显性的遗传缺陷综合征所致,绝大多数为低危险性的遗传性代谢酶基因的多态性或缺失所致。本文对这方面的研究进展作一简要综述。
Since the 1980s, molecular epidemiological studies have shown that about 5% of the population’s genetic susceptibility to cancer is caused by a dominant genetic defect syndrome. The vast majority are genetic polymorphisms of low-risk inherited metabolic enzyme genes. Due to lack. This article gives a brief overview of the research progress in this area.