引言离子选择电极是新型电化学测试器件在药物的有效成份分析,成品药质量控制、药理研究等方面也开展了广泛的应用1979年S.S.Hassan利用K_2P_bO_2与维生素B_1作用生成P_bS沉淀,以P_b~(2+)-ISE为指示电极。EDTA溶液为滴定剂进行电位滴定,间接求得维生素B_1的含量。1982年Selig Walter利用P_b~(2+)—ISE测定了丹参注射液中某些取代儿茶酚。 Introduction Ion-selective electrode is a new electrochemical test device in the active ingredient analysis of drugs, finished drug quality control, pharmacological research, also carried out a wide range of applications 1979 SSHassan K_2P_bO_2 and vitamin B_1 role in the formation of P_bS precipitation P_b ~ ( 2 +) - ISE is the indicator electrode. EDTA solution titration potentiometric titration, indirect determination of vitamin B_1 content. In 1982, Selig Walter used P_b ~ (2 +) - ISE to determine some substituted catechins in Danshen injection.