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自1978和1980年两份研究报告公布后,苯磺唑酮已用于防治心肌梗塞后的猝死。作者报告3例用苯磺唑酮治疗后发生可逆性急性肾功能不全患者。3例均为男性,年龄45~66岁,患急性心肌梗塞合并充血性心力衰竭,心衰用地高辛和利尿剂治疗后得以缓解。3例患者在心肌梗塞后于第8天、1个月和4个月,开始服用苯磺唑酮600~800mg/d,分次口服,以减少猝死的危险。患者均无肾脏病史,服药前肾功能亦
Since the publication of two studies in 1978 and 1980, benzezolidone has been used to prevent sudden death after myocardial infarction. The authors report three patients who developed reversible acute renal failure after treatment with tribenuron-methyl. Three patients were male, aged 45 to 66 years, suffering from acute myocardial infarction with congestive heart failure, heart failure with digoxin and diuretic therapy can be alleviated. Three patients started on day 8, 1 and 4 months after myocardial infarction and began taking benzezolone 600-800 mg / day orally in divided doses to reduce the risk of sudden death. No history of renal disease in patients with medication before renal function also