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目的研究子宫内膜癌患者的临床分期、肿瘤组织分化和肌层浸润深度、受体状态与预后的关系。方法对57例子宫内膜癌患者进行随访,40例随诊满5年。50例患者的石蜡标本应用免疫组化LSAB法测定雌激素受体(ER)和孕激素受体(PR)。结果随访提示5年生存率随肿瘤分化程度低、肌层浸润深和临床分期晚而下降,ER和PR阳性率也呈下降趋势。受体阳性者5年生存率高。结论组织分化程度、肌层浸润、临床分期和受体状态可作为观察预后的指标。
Objective To study the clinical stage, tumor tissue differentiation and depth of myometrial invasion, the relationship between receptor status and prognosis in patients with endometrial cancer. Methods 57 cases of endometrial cancer were followed up, 40 cases were followed up for 5 years. Paraffin specimens from 50 patients were tested for estrogen receptor (ER) and progesterone receptor (PR) using immunohistochemical LSAB method. Results The follow-up showed that the 5-year survival rate decreased with the degree of tumor differentiation, deep myometrial invasion and clinical stage, and the positive rates of ER and PR also showed a decreasing trend. Recipient-positive 5-year survival rate is high. Conclusions Tissue differentiation, myometrial invasion, clinical stage and receptor status can be used as indexes to observe prognosis.