笔者自1984年以来,从事妇幼保健工作。从实践中总结了广大哺乳期妇女在患病时应禁用哪些药物,现作一简述: 1 氯霉素 可通过乳汁进入婴儿体内,逐渐蓄积,使婴儿出现面色苍白、口唇紫绀、呼吸不规则、呕吐、腹胀等临床症状,即灰婴综合征,有致死的危险。氯霉素有导致婴儿再生障碍性贫血的可能。 2 红霉素 静脉滴注后乳汁中红霉素浓度为血清浓度的4倍,哺乳后婴儿可出现恶心、呕吐、腹痛等肠道反应,损害婴儿的肝脏,有时发生皮疹。 3 吗啡及哌替啶 婴儿呼吸中枢对吗啡极其敏感,长期用此类药物的哺乳期妇女,通过乳汁使婴儿呼吸浅慢以致停止。 4 碘剂 可通过乳汁进入婴儿体内,久之可造成甲状腺素合成减少;再经垂体促甲状腺作用,使婴儿甲状腺 Since 1984, I have been working in maternal and child health care. Summary from the practice of the majority of lactating women in the disease should be disabled which drugs, now make a briefing: 1 chloramphenicol can enter the baby through the milk, gradually accumulate, so that babies pale, lips cyanosis, irregular breathing , Vomiting, bloating and other clinical symptoms, that gray baby syndrome, there is a risk of death. Chloramphenicol has the potential to cause aplastic anemia in infants. 2 erythromycin intravenous erythromycin in milk after the concentration of 4 times the serum concentration, breastfeeding infants may appear nausea, vomiting, abdominal pain and other intestinal reactions, damage to the baby’s liver, sometimes rashes. 3 The morphine and pethidine infant respiratory centers are extremely sensitive to morphine. Lactating women who use these drugs for long periods of time stop their babies breathing too slowly through milk. 4 iodine can enter the baby through the milk, for a long time can lead to reduced thyroid hormone synthesis; and then by the pituitary thyroid effect, the baby thyroid