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目的了解抗结核药副作用发生及防治。方法回顾性分析 6 84例肺结核患者的临床资料。结果抗结核药出现副作用 2 71例( 39.6 %) ,以肝损害、胃肠反应、听神经损害、血液学异常、关节痛及皮肤过敏等为主 ( 96 .3%) ,有的因副作用致终止治疗者 95例( 13.9%)。 71%的副作用出现于给药的 2月内。结论抗结核药物引起的副作用常见 ,应予以重视。
Objective To understand the occurrence and prevention of side effects of anti-TB drugs. Methods The clinical data of 6 84 pulmonary tuberculosis patients were retrospectively analyzed. Results Twenty-one (39.6%) patients had side effects of antituberculotics. The main adverse reactions were liver damage, gastrointestinal reaction, auditory nerve damage, hematological abnormalities, joint pain and skin allergy (96.3%), Treatment of 95 patients (13.9%). 71% of the side effects occurred within 2 months of administration. Conclusion The side effects caused by anti-TB drugs are common and should be paid attention to.