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Valtrate和didrovaltrate是从蜘蛛香(Valeriana wallichii)中分离的2种单萜酯,关于其对培养的肝细胞瘤的超微结构的影响已有报道,这两种化合物有细胞毒作用,抑制肿瘤细胞中DNA和蛋白质的合成。本研究采用扫描和透射电子显微镜对细胞死亡之前进行观察,发现这两种化合物能引起
Valtrate and didrovaltrate are two kinds of monoterpene esters isolated from Valeriana wallichii, and their effects on the ultrastructure of cultured hepatoma have been reported. These two compounds have cytotoxic effects and inhibit tumor cells. DNA and protein synthesis. This study used scanning and transmission electron microscopy to observe the cells before they died. It was found that these two compounds can cause