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盾叶薯蓣(DioscoreazingiberensisC.H.Wright)根茎正丁醇提取物呈现显著的灭钉螺活性。由生物活性引导法分离得到两种具有灭钉螺活性的甾体皂甙,经化学和光谱方法分析,确定它们为纤细皂甙和盾叶皂甙A。其中,纤细皂甙72h灭钉螺率为98%(5mg/L),盾叶皂甙A72h灭钉螺率为96%(5mg/L)。首次报道了灭钉螺活性。
Dioscorea zingiberensis C.H.Wright rhizome n-butanol extract showed significant snail activity. Two biologically active steroidal saponins with insecticidal activity were isolated by bioactivity-guided method. The chemical constituents were identified as saponin A and saponin A by chemical and spectral methods. Among them, sylosin 72h off nails snail rate of 98% (5mg / L), saponins saponin A72h off nails rate of 96% (5mg / L). For the first time reported off snail activity.