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该文对腹痛儿童中幽门螺旋菌(HP)的发病率作了前瞻性研究,并对HP感染与临床、内窥镜和组织学之间的联系作了调查。材料与方法1988年11月～1991年6月对270例,平均年龄9.1±3.5 岁腹痛2周以上、有或无呕吐和呕血的患儿进行检查。所有患儿在两周内未接受能影响检查结果的药物(抗生素、铋剂、制酸剂)均剔除。对家族消化性溃病史进行调查。用内窥镜作上消化道检查,取胃窦标本放入3种培养基培养。当菌落生长后,进行革兰氏染色和氧化氢酶、氧化酶、脲酶试验。革兰氏染色和三种酶试验均阳性者为阳性。第二份及以后的活检标本固定后经组织学检
The paper prospectively studied the incidence of Helicobacter pylori (HP) in children with abdominal pain and investigated the link between HP infection and clinical, endoscopic, and histologic findings. Materials and Methods From November 1988 to June 1991, 270 patients with mean age of 9.1 ± 3.5 years with abdominal pain of more than 2 weeks who had or without vomiting and hematemesis were examined. All children were excluded from the medication (antibiotics, bismuth, antacids) that could affect the test results within two weeks. Family history of peptic ulcer disease investigation. With endoscopy for upper gastrointestinal tract, take sinusoidal specimens into three kinds of culture medium. After colony growth, Gram stain and catalase, oxidase, and urease tests were performed. Gram stain and three enzyme tests were positive for those who were positive. The second and subsequent biopsy specimens were fixed by histological examination