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5. Theoretical studies of interaction models of human acetylcholine esterase with different inhibitors

Theoretical studies of interaction models of human acetylcholine esterase with different inhibitors

来源 :中国科学：化学英文版 | 被引量 : 0次 | 上传用户：BESTWANGLOVE

【摘 要】

：

Alzheimer’s disease(AD) is a progressive neurodegenerative disorder and one of the most common causes of dementia in the elderly.Acetylcholine esterase inhibit

【作 者】

：

QingChuan Zheng (1)  HuiYing 

【机 构】

：

1.StateKeyLaboratoryofTheoreticalandComputationalChemistry

【出 处】

：

中国科学：化学英文版

【发表日期】

：

2009年11期

【关键词】

：

Alzheimer’s disease ACETYLCHOLINE ESTERASE INHIBITOR DOCKING Alzheimer’s disease 

【基金项目】

：

Supported by the Specialized Research Fund for the Doctoral Program of Higher Education (Grant No. 20070183046),the Specialized Fund for the Basic Research of Jilin University (Grant No. 200810018)

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Alzheimer’s disease(AD) is a progressive neurodegenerative disorder and one of the most common causes of dementia in the elderly.Acetylcholine esterase inhibitors(AChEI) are the main drugs used in the treatment of AD.In this work,docking studies have been

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