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目的:血小板的活化与聚集在心血管疾病的发病机制中起到非常重要的作用。作者曾通过社区动脉粥样硬化风险(ARIC)颈动脉MRI研究的数据对血小板糖蛋白Ⅲa(Leu33Pro)单核苷酸多态性(SNP)与颈动脉斑块形态以及血小板标记物表达之间的相关性进行研究。
Objective: Platelet activation and aggregation play a very important role in the pathogenesis of cardiovascular diseases. The authors used data from the Carotid Artery MRI Study of Community-Atherosclerosis Risk (ARIC) to determine the relationship between single nucleotide polymorphism (SNP) of platelet glycoprotein IIIa (Leu33Pro) and carotid plaque morphology and platelet marker expression Relevance study.