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职业性手臂振动病(Hand-arm vibration disease,HAVD)是由于长期从事手传振动作业而引起以手部末梢循环和(或)手臂神经功能障碍为主的疾病,并能引起骨关节-肌肉功能的损伤~([1]),在我国已列为法定职业病。HAVD血管损伤方面的病理生理机制主要包括血管结构和功能的异常~([2]),其发生与血管壁(特别是内皮细胞)中的活性物质、神经递质、细胞因子、代谢酶等变化密切相关~([3]),机体在接触振动早期出现的
Occupational hand-arm vibration disease (HAVD) is a disease mainly caused by the circulation of the hand and / or the nerve dysfunction of the arm caused by the long-term hand vibration work and can cause the bone-joint-muscle function The injury ~ ([1]), in our country has been classified as a statutory occupational disease. The pathophysiological mechanisms of vascular damage in HAVD mainly include abnormalities of vascular structure and function ([2]), which are related to the changes of active substances, neurotransmitters, cytokines and metabolic enzymes in the vascular wall (especially endothelial cells) Closely related to ~ ([3]), the body appeared early in contact with vibration