目的观察窒息缺氧与新生儿黄疸的关系。方法测定 10 6例足月新生儿的血清胆红素值 ,并按轻度窒息缺氧组、重度窒息缺氧组和无窒息缺氧组分组进行比较。结果高胆红素血症发生率 3组分别为 2 8.6%、14 .7%、46.7% ,有显著性差异 (P<0 .0 5 ) ,其中重度窒息缺氧组明显低于无窒息缺氧组 (P<0 .0 1) ;血清胆红素 3组分别为 (184.7± 48.3 )μmol/L、(15 3 .2± 48.9)μmol/L、(2 0 9.6± 49.7)μmol/L,轻度窒息缺氧组低于无窒息缺氧组 (P<0 .0 5 ) ,重度窒息缺氧组明显低于轻度窒息缺氧组 (P<0 .0 1)和无窒息缺氧组 (P<0 .0 1)。结论窒息缺氧时氧自由基的产生可能使新生儿黄疸减轻、高胆红素血症发生率降低 Objective To observe the relationship between asphyxia and neonatal jaundice. Methods Serum bilirubin values ​​of 106 full-term neonates were measured and compared according to mild apnea hypoxia group, severe asphyxia hypoxia group and no asphyxia hypoxia group. Results The incidence of hyperbilirubinemia in 2 groups was 28.6%, 14.7% and 46.7%, respectively (P <0.05), and the incidence of hyperbilirubinemia in severe hypoxia and hypoxia group was significantly lower than that without asphyxia (184.7 ± 48.3) μmol / L, (15.32 ± 48.9) μmol / L, and (209 ± 49.7) μmol / L, respectively , Mild asphyxia group was lower than that of asphyxia group (P <0.05), severe asphyxia group was significantly lower than that of mild asphyxia group (P <0.01) and asphyxial hypoxia group Group (P <0. 01). Conclusions Oxygen free radicals during asphyxia and hypoxia may reduce neonatal jaundice and reduce the incidence of hyperbilirubinemia