为观察静脉化疗及腹腔化疗对细胞免疫的影响,选择较好的化疗方案,自1994年起,连续对18例大肠癌根治术后早期静脉化疗及21例腹腔化疗病人进行观察,行5－FU加左旋咪唑方案化疗.通过化疗前后抽血检查T细胞亚群比例及NK细胞比例的变化,发现腹腔化疗组上述指标无明显下降,静脉化疗组下降明显,证明腹腔化疗对细胞免疫抑制较重.认为:腹腔化疗是大肠癌根治术后较为理想的辅助治疗措施“,”The effects of intraperitoneal chemotherapy on cell-mediated immunity were compared and the more effective method was identified.Eighteen patients were treated with intravenous chemotherapy and 21 patients were treated with intraperitoneal chemotherapy.5-Fu and Levamisole were administered.The ratio of subgroup T cells and NK cells was determined using haemospasia before and after chemotherapy.It was discovered that the ratio declined less in the intraperitoneal cases than in the intravenous cases.This indi...