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目的:探讨左乙拉西坦添加治疗难治性癫痫的疗效和安全性。方法:回顾性分析了35例左乙拉西坦添加治疗的难治性癫痫患者,随访3～18个月,观察其疗效及不良反应。结果:左乙拉西坦添加治疗难治性癫痫总有效率为48.6%,对部分性发作和全面性发作的疗效无显著差异。不良反应发生率为31.5%,无严重不良反应。结论:左乙拉西坦是一种安全有效的难治性癫痫治疗药物,可以用于难治性癫痫的添加治疗。
Objective: To investigate the efficacy and safety of levetiracetam in the treatment of refractory epilepsy. Methods: A retrospective analysis of 35 patients treated with levetiracetam refractory epilepsy, followed up for 3 to 18 months to observe the efficacy and adverse reactions. Results: The total effective rate of levetiracetam in the treatment of refractory epilepsy was 48.6%, and there was no significant difference in the curative effect between partial and complete seizures. The incidence of adverse reactions was 31.5%, no serious adverse reactions. Conclusion: Levetiracetam is a safe and effective treatment of refractory epilepsy, which can be used for the treatment of refractory epilepsy.