中耳渗液中生物活性化合物(酶及其抑制剂、炎症介质、补体成份、纤溶和激肽系统)的研究已受到明显重视,这类化合物来自血液的有形成份(尤其是白细胞)、受损伤的组织以及微生物,可影响和促进中耳组织破坏及其它并发症的发展,使中耳炎由急性转为慢性。作者对82例中耳炎患者(急性浆液性4例, Significant emphasis has been placed on studies of bioactive compounds (enzymes and their inhibitors, inflammatory mediators, complement components, fibrinolytic and kinin systems) in the middle ear effusion that come from the visible components of blood (especially leukocytes), Damaged tissues and microorganisms can affect and promote the destruction of the middle ear tissue and other complications, leaving otitis media from acute to chronic. The authors of 82 cases of otitis media (acute serous 4 cases,