肥厚型梗阻性心肌病患者常伴有二尖瓣反流，但其发生机制尚不完全清楚。目前的研究发现二尖瓣叶异常、乳头肌移位与舒张晚期血流将瓣叶推移入左室流出道所导致的二尖瓣对合面积变小是其主要原因。“,”Mitral regurgitation is often accompanied by obstructive hypertrophic cardiomyopathy, whose mechanism is not entirely clear at present.The current studies found that mitral regurgitation was mainly attributed to the reduced leaflet coaptation resulted by mitral leaflet abnormalities, displacement of papillary muscle and flow force during late diastole pulling the leaflet into the left ventricular outflow.