茶芎(抚芎)的药理研究(简报)

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茶芎又名抚芎,为伞形科植物(Ligusticum slnense),药用根茎,是江西特产中药材之一。临床上与川芎混用。离体蛙心灌流茶芎乙醇提取物浴槽浓度0.02mg/ml心博幅度略增大,心率略减慢,心输出量无明显影响,浓度增大,对心脏呈控制作用。茶芎中分离的挥发油,生物碱结晶1号对心脏搏动有明显抑制作用。离体豚鼠灌流心脏,茶芎乙醇提取物小剂量心跳幅度略增大,大剂量则减少,心率无明显影响,无论小剂量或大剂量,冠脉流量均增加。茶芎挥发油及生物碱结晶1号0.02mg注 The tea plant, also known as Fuyu, is an umbrella plant (Ligusticum slnense), a medicinal rhizome that is one of the specialty Chinese medicinal materials in Jiangxi. Clinically mixed with Chuanxiong. In vitro frog heart perfusion ethanol extract of tea broth concentration 0.02mg/ml slightly increased the heart rate, heart rate slightly slowed, cardiac output had no significant effect, the concentration increased, showed a control effect on the heart. The volatile oil isolated from the tea pods, Alkaloid Crystal No. 1 has a significant inhibitory effect on the heart beat. In isolated guinea pig perfused hearts, the amplitude of small-dose heartbeats of ethanol extracts from tea leaves increased slightly, while high doses decreased, and there was no significant effect on heart rate. Both small-dose and high-dose coronary blood flow increased. Camellia volatile oil and alkaloid crystal No. 1 0.02mg Note
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