完全性葡萄胎的染色体分析最初显示为46,XX核型。当前文献报告的173例中159例(91.9％)性染色体是 XX,14例(8.1％)是 XY。10例 XY 葡萄胎作了充分的随访,其中2例后来成为绒癌。由于推测 XY 葡萄胎特别易恶变,因而对葡萄胎的广泛研究引起注意,重点在于 Y 染色体的发生率和危险因素。这方面的研究已扩展到恶性滋养叶肿瘤。 Chromosome analysis of complete moles initially showed 46, XX karyotypes. Of the 173 reported in the current literature, 159 (91.9%) of the sex chromosomes were XX and 14 (8.1%) were XY. Ten cases of XY mole were fully followed, two of which later became choriocarcinoma. Due to speculation that XY mole is particularly susceptible to malignant transformation, extensive attention has been given to hydatidiform moles, with an emphasis on the incidence of Y chromosomes and risk factors. Research in this area has been extended to malignant trophoblastic tumors.