论文部分内容阅读
自1989年5月至1996年1月采用改良VBP方案作为宫颈局部肿瘤是巨块型（＞4cm）宫颈癌病例的第一线治疗共48人，142个疗程，无致命性毒性反应，获得了85％以上的有效率，完全缓解达45％，使48例原本只能放疗的患者有41例得以手术根治，而且手术切缘无残瘤。手术标本的病理学评价Ⅲ,Ⅳ级者占鳞癌病例的54％，占临床反应者的63％。淋巴结阳性率为12．1％。辅助化疗组5年生存率79.1％，对照组仅50.8％（P＜0.005）。
Since May 1989 to January 1996 with modified VBP regimen as a local tumor of the cervix is a large block (> 4cm) of first-line treatment of cervical cancer in a total of 48 people, 142 courses, non-fatal toxicity, obtained More than 85% of the effective rate, the complete relief of up to 45%, so that 48 cases of patients with radiotherapy alone had 41 cases of radical surgery, and surgical margin without residual tumor. Pathological evaluation of surgical specimens Ⅲ, Ⅳ grade accounted for 54% of squamous cell carcinoma cases, accounting for 63% of clinical responders. The positive rate of lymph node was 12.1%. The 5-year survival rate was 79.1% in the adjuvant chemotherapy group and 50.8% in the control group (P <0.005).