论文部分内容阅读
卫生部关于11种下乡成药的检验标准及方法中所載瘡药膏(每100g含磺胺5g,凡士林95g)及磺胺噻唑眼药膏(每100g含磺胺噻唑5g,黄凡士林95g)的測定方法为:精密秤取約10g样品,加HGI 10 ml及蒸溜水100 ml,加热溶解后冷却,用玻棒將凝固的凡士林推至燒杯璧,加冰块約15g,用0.1 MNaNO_2滴定(药检工作通訊,1卷2期上辽宁药检所介紹的方法亦相似)。但我們在应用于磺胺噻唑药膏(处方为:磺胺噻唑5g,氧化鋅5g,魚肝油1g,凡士林加至100g,並含有羊毛脂)定量时,却發現含量偏低,一式二份誤差大(有时則結果較近),虽延長加热时间(如半小时)並不断攪拌,結果仍不好。曾將巳滴定至終点的溶液連同基质再加热溶解,攪拌,放冷再滴定,又能消耗少量
The Ministry of Health’s method for the determination of 11 kinds of medicines for the countryside, including sore ointment (containing 5 g of sulfonamide per 100g, petroleum jelly of 95 g) and sulfithiazole eye ointment (5 g of sulfathiazole and 100 g of yellow vaseline) per 100g, is the following: Take about 10g sample on precision scale, add HGI 10 ml and distilled water 100 ml, heat and dissolve and cool. Use a glass rod to push the solidified petrolatum to the beaker 璧, add ice cubes about 15g, titrate with 0.1 M NaNO 2 (Drug test work communication, 1 The method introduced by Liaoning Drug Testing Institute in Volume 2 is similar.) However, when we applied sulfathiazole ointment (prescription: sulfathiazole 5g, zinc oxide 5g, cod liver oil 1g, petrolatum to 100g, and lanolin), the content was found to be low, and the error was high in two copies (sometimes The result is closer. Although the heating time (eg half an hour) is extended and stirring is continued, the result is still not good. The solution that had been titrated to the end point with the matrix was reheated, dissolved, stirred, allowed to cool and then titrated, and consumed a small amount of