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本文总结了许多茶碱抑制移植排斥反应作用的实验和临床结果,同时分析了茶碱各种可能的免疫调节机制,提出了通过多途径调节的观点,最后预期了茶碱在移植免疫领域的前景;对茶碱的量效关系、时效关系和联合用药问题有必要作进一步的探讨。
This review summarizes the many experimental and clinical results that theophylline inhibits graft rejection and analyzes various possible immunomodulatory mechanisms of theophylline and proposes a multimodal perspective that predicts the future of theophylline in transplantation immunology ; The theophylline dose-effect relationship, the relationship between age and the need for further study of drug combination.