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目的掌握海南省中晚期妊娠期孕妇尿碘水平,评价海南省孕妇碘营养状况,为适时采取针对性防治措施和科学调整干预策略提供依据。方法 (1)按“人口比例概率抽样方法(PPS)”在全省范围内确定30个调查点,采取单纯随机抽样方法从每个调查点中抽取1所小学,随机抽取50名8~10岁学生,学校所在乡20名孕妇,采集学生和孕妇24 h任意尿液,检测碘含量。(2)采用整群随机抽样每市县按东、西、南、北、中划分5个抽样片区,在每个片区各随机抽取1个乡,在每个乡随机抽取4个村,每个村随机抽检15户居民食用盐,检测碘含量。(3)根据碘盐覆盖和儿童尿碘水平情况,分析不同地区、不同妊娠期孕妇碘营养水平。结果全省孕妇尿碘中位数是130.5μg/L,妊娠中、晚期的尿碘分别是130.5μg/L、132.1μg/L;西部沿海、内陆山区、东部沿海地区孕妇尿碘分别是130.2μg/L、132.7μg/L、132.0μg/L;儿童尿碘中位数在<100μg/L、100~200μg/L、≥200μg/L地区的孕妇尿碘中位数分别是120.8μg/L、130.4μg/L、132.0μg/L;同一地区儿童尿碘水平与孕妇尿碘之间没有相关性。结论海南省不同妊娠期孕妇碘营养不足,密切关注孕妇的碘营养水平,预防新生儿受到碘缺乏的危害。
Objective To understand the level of urinary iodine in pregnant women of middle and late pregnancy in Hainan Province and to evaluate the iodine nutrition status of pregnant women in Hainan Province so as to provide evidence for timely prevention and control measures and scientific adjustment of intervention strategies. Methods (1) According to “Population Probability Sampling Method (PPS)”, 30 survey points were determined in the whole province. A simple random sampling method was used to select one primary school from each survey point and randomly selected 50 8 ~ 10-year-old students, 20 pregnant women in the township of the school, students and pregnant women 24 h random urine, iodine detection. (2) Random cluster sampling is adopted. Each county is divided into 5 sampling areas by east, west, south, north and north, randomly select 1 village in each area and 4 villages in each village randomly, each Village random sampling of 15 households salt consumption, detection of iodine content. (3) According to iodine salt coverage and urinary iodine levels in children, analysis of iodine nutrition level in different regions and different pregnant women. Results The median urinary iodine of pregnant women in the province was 130.5μg / L, urinary iodine of middle and late pregnancy was 130.5μg / L and 132.1μg / L, respectively. The urinary iodine of pregnant women in the coastal areas of western China, inland mountains and eastern China were 130.2 μg / L, 132.7μg / L and 132.0μg / L respectively. The median urinary iodine in pregnant women with urinary iodine <100μg / L, 100-200μg / L and ≥200μg / L was 120.8μg / L , 130.4μg / L and 132.0μg / L respectively. There was no correlation between urinary iodine level in pregnant women and urinary iodine in children in the same area. CONCLUSION: Iodine nutrition is not sufficient in pregnant women of different pregnancy stages in Hainan Province, and the iodine nutrition level of pregnant women is closely monitored to prevent neonates from being affected by iodine deficiency.