随着对青光眼发病机制的不断深入研究,青光眼的概念已经不仅仅是传统的高眼压性眼病,而是一种多因素导致的视神经退行性病变,其中包括高眼压机械损伤、眼血流量减少、缺血/再灌注损伤、氧化应激(OS)损伤、谷氨酸盐兴奋性中毒及异常免疫反应等。在此讨论近年来关于OS对青光眼发病的实验研究,总结了与OS有关的治疗策略。 With the continuous study of the pathogenesis of glaucoma, the concept of glaucoma has not only the traditional ocular hypertension, but a multifactorial optic neurodegenerative disease, including mechanical ocular hypertension, ocular blood flow Reduction, ischemia / reperfusion injury, oxidative stress (OS) damage, glutamate excitotoxicity and abnormal immune responses. In this discussion on the OS in recent years, the incidence of glaucoma experimental study, summed up the OS-related treatment strategies.