CLINICAL OBSERVATION OF 144 CASES OF RHEUMATOID ARTHRITIS TREATED WITH GLYCOSIDE OF RADIX TRIPTERYGI

来源 :Journal of Traditional Chinese Medicine | 被引量 : 0次 | 上传用户:jeff2001
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Satisfactory results have been obtained inthe treatment of 144 cases of rheumatoid arthri-tis with glycoside extracted from Radix Trip-terygium Wilfordii.Total effective rate was93.3%(clinical remission 17.6%,effective 37.5%,improvement 38.2%).The course of treatmentwas three months,dosage 1-1.5 mg/kg per os.Side effects included mild gastrointestinal dis-turbances.There also occurred irregular men-struation and amenorrhea in female patients andgynecomastia in males.These adverse reactionssubsided after withdrawal of the drug.Clinicaland laboratory observation suggested that themechanism of the glycoside action was suppres-sion of cellular and humoral immunity. Satisfactory results have been obtained inthe treatment of 144 cases of rheumatoid arthri-tis with glycoside extracted from Radix Trip-terygium Wilfordii.Total effective rate was93.3%(clinical remission 17.6%,effective 37.5%,improvement 38.2%).The course of Treatmentwas three months, dosage 1-1.5 mg/kg per os.Side effects included mild gastrointestinal dis-turbances.There also occurred irregular male-struation and amenorrhea in female patients and gynecomastia in males.These were released aftersubsided after withdrawal of the drug.Clinicaland laboratory Observation suggested that the themechanism of the glycoside action was suppres-sion of cellular and humoral immunity.
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