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一、本文报告11例“淋巴肉瘤細胞型”白血病,占有病理証实的淋巴肉瘤患者25.0％。二、对11例的临床表現作了描述,除因肿瘤压迫的呼吸及循环等系統改变外,亦見肝肿大7例及脾肿大6例,同时有2例皮肤出現棕紅色斑疹,病理証实为細胞浸潤。三、除注意观察紅細胞及白細胞等改变外,对瘤細胞的形态亦应用瑞氏染色、相差显微鏡及螢光显微鏡进行检查均有特殊的变化,有助于此病的診断。四、在治疗中,各种药物的选用如氮芥、激素、AT—16等,应按疾病的表現分別对待。激素用于病情較急,氮芥用于病程慢者可能較好,AT16因例数少,尚不易肯定价值。注:淋巴肉瘤患者44例,系指均有病理証实者。此外,尚有临床診断者105例,总数为149例,則“淋巴肉瘤細胞型”白血病11例,占所有淋巴肉瘤患者的7.4％。
First, this article reports 11 cases of “lymphosarcoma-type” leukemia, accounting for 25.0% of patients with pathologically confirmed lymphosarcoma. Second, the clinical manifestations of 11 cases were described, in addition to the respiratory system due to tumor compression and other changes, but also see the hepatomegaly and splenomegaly in 7 cases, while 2 cases of brown red skin rash, Pathology confirmed as cell infiltration. Third, in addition to observe changes such as red blood cells and white blood cells, the morphology of the tumor cells also applied Wright staining, phase contrast microscope and fluorescent microscopy examination have a special change, contribute to the diagnosis of the disease. Fourth, in the treatment, the choice of various drugs such as nitrogen mustard, hormones, AT-16, etc., should be treated according to the performance of the disease. Hormones for acute illness, nitrogen mustard for slow course may be better, AT16 due to fewer cases, is not yet easy to affirmative. Note: 44 cases of lymphosarcoma, refers to both pathologically confirmed. In addition, there are 105 cases of clinical diagnosis, a total of 149 cases, the “lymphosarcoma” leukemia in 11 cases, accounting for 7.4% of all lymphosarcoma patients.